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Selenium reduces the proapoptotic signaling associated to NF-B pathway and stimulates glutathione peroxidase activity during excitotoxic damage produced by quinolinate in rat corpus striatum

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Moreover, progesterone enhances the release of gonadotropin-releasing hormone (GnRH) and increases the sensitivity of the pituitary gland to GnRH, thereby triggering an LH surge

After treatment with Vitamin U alone (100 mg/kg, b.wt, oral) alone, Vitamin-U alone (150 mg/kg, b.wt, oral) alone, Vitamin-U alone (150 mg/kg, b.wt, oral), Vitamin-U (100 mg/kg, b.wt) combined with Vitamin- E (200 mg/kg, b.wt, oral) and Vitamin-E (200 mg/kg, b.wt, oral) alone significantly increased SOD and GSH level and decreased LPO level

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