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Value assessment: Collectible value: Medium to High

The Philippines is one of the largest global cigarette markets, with an estimated 2010 volume of 101 billion cigarettes

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These breaks may cause genetic rearrangements and contribute to the advancement from Barretts esophagus to esophageal adenocarcinoma.[23] According to a recent study carried out in Sweden, it was found that Snus users who had never smoked had a higher risk of esophageal squamous cell cancer and a slightly elevated risk of noncardiac stomach cancer.[24] Ness Jensens study demonstrated that tobacco users had a higher susceptibility to developing gastroesophageal reflux disease (GERD) which in turn leads to esophageal stenosis, stricture formation and inflammation of the gastrointestinal (GI) tract.[25] Similarly, our study found that long-term use of SLT was associated with chronic UGI mucosal changes, including inflammation, erosions, and a lax gastroesophageal junction