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5557 Hoffmann et al 16 suggested that cigarette smoke induced morphologic changes in the COPD epithelium by significantly increasing the expression of Mfn1/2 and Opa1, which were accompanied by increased levels of the proinflammatory mediators such as IL-8, IL-6 and IL-1

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Farber, MD, MSPH Associate professor of pediatrics, pulmonary section, Baylor College of Medicine and Texas Children's Hospital Associate medical director, Texas Children's Health Plan chair, Tobacco Action Committee, American Thoracic Society Disclosures: Ask a clinical question and tap into Healio AI's knowledge base

95% CI 0.88 to 1.53) 56

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