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Smoking prevalence is also higher among adults living below the poverty level (28.8%)

Evol Int J Organic Evol 39(4):783791

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Modeling studies have estimated a 15% reduction in smoking within 40 years if menthol cigarettes are no longer available, the agency said, and those same studies estimate that 324,000 to 654,000 smoking-related deaths overall (92,000 to 238,000 among Black Americans) would be avoided over the course of 40 years

Or the person is just a rapid metabolizer at those enzymes, so something is making the clozapine speed away into norclozapine, lowering the clozapine levels