However, they are most effective and safest when used for their approved purposesprimarily for people with obesity or type 2 diabetes
When to contact your GP: Persistent or severe nausea/vomiting preventing adequate fluid intake Severe, persistent abdominal pain which could indicate pancreatitis New or worsening depression, anxiety, or suicidal thoughts Severe headaches or visual disturbances Unexplained cognitive changes or confusion Signs of hypoglycaemia (if taking alongside insulin or sulfonylureas) NICE guidance recommends regular monitoring during GLP-1 receptor agonist therapy
Additionally, other neurotrophic factors, such as glial cell line-derived neurotrophic factor (GDNF), contribute to the development, maintenance, and survival of neurons, glia, and oligodendrocytes
PEA is one of the most abundant endocannabinoids in the gut and is thought to play a key role in gut-brain axis
If abnormal TSH levels persist, Ill ask my clients to speak with their doctor about thyroid hormone treatment
