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Moreover, the discovery of antifibrotic drugs such as AZM, BC450, and PFD, along with the clinical use of pirfenidone and nintedanib, suggests that targeting specific E3 ligases and their downstream effectors could transform IPF management

For she of hearbes had great intendment, Taught of the Nymphe, which from her infancy Her nourced had in trew Nobility: There, whether it diuine Tobacco were, Or Panachea, or Polygony, She found, and brought it to her patient deare who al this while lay bleeding out his hart-bloud neare

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