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it is responsible for an enormous burden of disease, death and economic cost in the United States

Among those exposed to tobacco before birth or who began smoking during childhood or adolescence, participants who had a genetic predisposition to develop Type 2 diabetes and started smoking in childhood or adolescence had the highest risk of developing Type 2 diabetes

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Their effects on sperm are both well-documented and serious: Reduced sperm count: Smokers consistently show 15 to 25 percent lower sperm concentrations compared to non-smokers Impaired sperm motility: The ability of sperm to move progressively toward an egg is significantly reduced in men who smoke Abnormal sperm morphology: The proportion of normally shaped sperm is lower in tobacco users, reducing the chance of successful fertilisation Elevated sperm DNA fragmentation: This is perhaps the most critical effect