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Cristina Castillo, an archaeobotanist at University College London who also did not contribute to the new research, additionally suggests that the detection of betel nut use requires more evidence than just dental calculus

Menthol also interacts with nicotine in the brain to enhance the addictiveness of nicotine, making it harder for people to quit smoking, explained Rachel Grana Mayne, Ph.D., a program director in NCI's Tobacco Control Research Branch

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