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Studies were screened independently by two reviewers for eligibility, extracted data, and assessed risk of bias

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Phase 2 and interim phase 3 clinical trial data demonstrate robust effectiveness of GLP-1 RAs in achieving MASH resolution, with semaglutide showing additional promise for fibrosis improvement in the ongoing ESSENCE trial

[8] In the United Kingdom it is listed as less preferred than metformin or a sulfonylurea

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