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REHQR Program Measures and Topics for Future Consideration We refer readers to section XIV.B

Stress, Cortisol, and Oxidative Burden Chronic psychological stress elevates cortisol and other stress hormones, which increase oxidative stress through multiple mechanisms including promotion of inflammatory cytokine production, impairment of antioxidant enzyme function, increased metabolic rate and oxygen consumption, and disruption of sleep and other restorative processes

Wei C, Kim IK, Li L, Wu L, Gupta S

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The peptide exists naturally in human plasma, and supplemental doses remain well below toxic thresholds