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Nanomedicine targeting GLUT1 to block glucose supply As a key transporter responsible for transmembrane glucose flux in tumor cells, GLUT1 is synthesized in the rough endoplasmic reticulum [60]

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Although a full understanding of the mechanism of OCTN2 transport will require additional structural characterisation, particularly of outward-facing conformations, the data presented here provides a strong foundation for our proposed mechanism

similarly, it was reported that ob/ob mice (Garca-Ruiz and Fernndez-Checa 2018) as well as mice fed a high-fructose diet (Li and Lu 2018) exhibited a decrease in the GPx activity as compared to controls, respectively