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In cases of mild to moderately active CD, alterations in tight junction structure and barrier dysfunction were associated with downregulation of claudins-5 and 8 and an upregulation of claudin-2 [90]

Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors

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Pelaseyed T, Bergstrm JH, Gustafsson JK et al (2014) The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system