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The preclinical evidence reveals that DHA suppresses non-small-cell lung cancer via the RvD1/miR-138-5p/FOXC1 pathway, providing mechanistic support for clinical applications (Figure 4)

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Expression of a specific VEGF isoform in an otherwise non-tumorigenic, non-VEGF expressing melanoma cell line results in an aggressive tumor with a highly extensive supporting vasculature, suggesting its undisputed role in promoting angiogenesis (88)

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