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The rate of substrate turnover is measured by change in absorbance and is proportional to LDH release and is corresponds to cellular stress due to toxicity
In our cEDS cohort, headache/migraine and chronic fatigue were referred respectively by ~ 41% and ~ 36% of cEDS patients, especially by adults even though not statistically significant, whereas impaired memory and concentration and paresthesia were both more recurrent in adults (~ 40% vs ~ 10%)
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The Dark Knight takes a different approach, in which the Jokers relationship to the hero is less important than his relationship to the film as a whole
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