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Wait just as long as you would with regular cigarettesat least 72 hours, preferably longer

Smoking, even for a few years, can have a significant effect on facial ageing

Google 'TV tropes Littlest Cancer Patient', please

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Otherwise, there is some degree of inference, since individuals usually have some variability across their cognitive abilities and skills pre-injury, and some changes may have happened in the intervening decades as a result of normal aging and the drug and alcohol use (although, with years of being clean and sober, some of the latter may have been mitigated)