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Co-use was relatively stable across the different periods. Writing in the journal of Addictive Behaviors, the researchers said that the evolving trends in use of the two substances could be evidence of a substitution effect amid changing harm perceptions, evolving legislation, and shifting norms. The rising cannabis-only use across groups parallels the expanding state-level recreational cannabis legalization, increasing accessibility and normalization, the paper says

The membranes in your nose and sinuses produce mucus that acts as a sort of blanket to help protect your respiratory system

One aspect of your nervous system is the Phrenic nerve, which is connected to your diaphragm (pronounced dai-uh-fram)

The resulting lipid peroxidation further damages hepatocytes, leading to inflammation and cell death