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4.4 Sulfur-containing amino acid metabolism and renal protection 4.4.1 Metabolic fate of methionine and cysteine Sulfur-containing amino acids (methionine and cysteine) play critical roles in maintaining redox balance and producing protective gaseous signaling molecules (140)

Studies have also revealed a relationship between poor sleep quality and HPA activation, which usually results in cortisol production

2017;21(5):580-591.e7

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Abbreviations PD: Parkinsons disease CNS: Central nervous system SCFA: Short-chain fatty acid TLR: Toll-like receptor LPS: lipopolysaccharide BBB: Bloodbrain barrier HDAC: Histone deacetylase REM: Rapid eye movement SNpc: Substantia nigra pars compacta ENS: Enteric nervous system GI: Gastrointestinal ROS/RNS: Reactive oxygen and nitrogen species FMT: Fecal microbiota transplantation GALT: Gut-associated lymphoid tissue AHR: Aryl hydrocarbon receptor SAAs: Seed-amplification assays TNF-: Tumor necrosis factor-alpha References Su D, Cui Y, He C, Yin P, Bai R, Zhu J, et al