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In the present investigation, we found that miR-125a-5p is highly expressed in lung tissues of smokers and smokers with COPD/emphysema, and the degree of cellular senescence increases with time of exposure

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So, is tobacco a gateway drug

Methods Overview For the present study, we used a meta-analytic tool, MR-BRT (metaregressionBayesian, regularized, trimmed), to estimate the doseresponse risk curves of the risk of a health outcome across the range of current smoking levels along with uncertainty estimates 28

E-cigarette Use Among Youth and Young Adults: A Report of the Surgeon General