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Trial management Under the supervision of the qualified investigator (QI) at each site, research staff will be responsible for day-to-day conduct of the trial

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Many of the reports of explosions do not identify the manufacturers of e-cigarettes that have the highest explosion risk

Until recently, genetic testing was principally based on (serial) single-gene testing by Sanger sequencing, i.e., analysis of COL5A1 is performed first, followed by COL5A2 analysis and then gene-targeted copy number variant analysis to identify large deletions or duplications

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