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Severe gastroparesis may worsen with GLP-1 agonist use
Clinical Evidence: What Research Shows About Combination Approaches Tirzepatide monotherapy has demonstrated significant weight loss in clinical trials: approximately 20-23% body weight reduction over 72 weeks in the SURMOUNT trials, depending on dose
Key Takeaways: Rapid adoption is driving better access, but irrational, unsupervised use is raising red flags
Obesity is a chronic disease, and for many patients, ongoing medication is appropriate management, the same way someone with hypertension stays on blood pressure medication indefinitely
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