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Monfort P, Cauli O, Montoliu C, Rodrigo R, Llansola M, Piedrafita B, El Mlili N, Boix J, Agust A, Felipo V (2009) Mechanisms of cognitive alterations in hyperammonemia and hepatic encephalopathy: therapeutical implications

338,339 In contrast, patients with T1DM often benefit from insulin therapy regarding neuropathic outcomes, as they typically do not exhibit significant insulin resistance

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However, some patients outside these parameters may also benefit when these medications are used safely under medical supervision for weight management and metabolic health