In research models, elevated NNMT activity has been associated with: lower NAD levels, with downstream effects on mitochondrial energy production
Available from: Jett, L., Lger, R., Thibaudeau, K., Benquet, C., Robitaille, M., Pellerin, I., Paradis, V., van Wyk, P., Pham, K., & Bridon, D
It helps regenerate damaged nerves, improves nerve signal transmission, and promotes the production of healthy red blood cells
Then, in 2015, Lee and colleagues identified a previously overlooked open reading frame within the 12S ribosomal RNA gene of mtDNA and found that it encodes a functional peptide, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) [1]
However many of these symptoms are general and can result from a variety of medical conditions other than vitamin B12 deficiency