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doi: 10.15585/mmwr.mm6901a2 303 PailO.LinM

VMAT2 exploits this H gradient via protonmonoamine exchange to actively transport cytosolic monoamines into the vesicle against their concentration gradient, enabling vesicular storage and subsequent regulated neurotransmitter release

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If your demand for glutathione is significant, eventually your body wont be able to keep up, and your glutathione levels will slowly become depleted