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3.3.4 MGBA alterations and pathophysiological mechanisms in anxiety Rodent models of anxiety disorders provide causal evidence that stress exposure disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance (Bear et al., 2021)

For many, the morning before breakfast is ideal to support daytime energy and mental clarity, but taking it at night is also effective if it is at least two hours after dinner to aid nighttime detoxification and repair

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Weeks of suboptimal dosing do not just mean slower progress

Other Health Benefits of Vitamin B12 While the focus of this article is on sleep, it's worth noting that Vitamin B12 offers a range of other health benefits