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Diets high in whole, minimally processed foods help support this natural response, while highly processed diets may blunt GLP-1 activity over time, Bannan explains

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36 In people with type 2 diabetes and established cardiovascular disease, two years of low-dose semaglutide (0.5 or 1 mg) reduced the risk of a composite outcome of cardiovascular death, nonfatal myocardial infarction or nonfatal stroke by 26%, primarily driven by stroke reduction

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Cells were cultured at 37 C in Dulbeccos modified Eagles medium (DMEM) + GlutaMax 1965 (Gibco) supplemented with 10% fetal bovine serum and 1% penicillinstreptomycin in a humidified 10% CO 2 incubator