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Bipolar disorder similarly exhibits disruption of the Firmicutes / Bacteroidetes ratio and reduced -diversity, featuring increased Streptococcaceae and Bacteroidaceae abundance contrasting with depletion of anti-inflammatory commensals such as Faecalibacterium ( 249).Among neurodegenerative disorders, Parkinsons disease shows increased abundance of Lactobacillus and Bifidobacterium with concurrent reduction in Faecalibacterium , Coprococcus , and Blautia ( 250, 251), where decreased Blautia abundance correlates with clinical severity and reduced fecal butyrate levels (252)

10.1016/j.colsurfb.2018.09.065 Colloids Surf B Biointerfaces

DOI Kang YA, Choi HR, Na JI, et al

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92 Thus, aspartate is a limiting factor for growth under hypoxic conditions