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3.2.3.2 Caffeic acid phenethyl ester (CAPE) CAPE, a natural antioxidant, possesses beneficial roles in cadioprotective, neuroprotective and renoprotective effects ( 3.2.3.3 Astaxanthin Astaxanthin, a natural non-toxic product in most of marine organisms, exhibits wide biologic properties, such as strong antioxidant, anti-apoptotic and anti-inflammatory activities, for its unique structure ( via its antioxidant activities in several kidney diseases, such as DKD ( 3.3 Promoting mitophagy Mitophagy is a specialized form of autophagy

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These technologies potentially allow the setup of an in vitro test system, which resembles the in vivo situation as closely as possible 27