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It is estimated to affect 112 million people worldwide by 2040 (Tham et al., 2014)

17% average weight loss in Phase 3 trials

However, glutaminase activity, glutamine content, and expression of the two astrocytic transporters Glt1 and GLAST were moderately increased in the knock-out animals

Keywords: health coaching, Obesity, anti-obesity medications, GLP-1, risk factors, weight loss A strong patient-centric coaching relationship and key coaching skills are essential to an effective intervention. Introduction The prevalence of obesity and related health consequences are well documented 1 with the American Medical Association recognizing obesity as a chronic disease in 2013

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