glutathione metal detox Glutathione: A key frontier of heavy-metal detoxification and tolerance in plants How Glutathione Supports Heavy Metal

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Lipid metabolism ROS significantly impacts cellular lipid metabolism by modulating fatty acid synthesis, decomposition, and oxidation [166], lipid catabolism [183, 184], and cholesterol metabolism [174]

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Studies have identified interactions between the mTOR signaling pathway and GPX4 expression, demonstrating that use of the classical ferroptosis activator, RSL3, can additionally block mTOR activation 9

Miyazawa T, Nakagawa K, Kudo M, Muraishi K, Someya K