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Reducing GSH biosynthesis generates replication stress in T315I-Bcr-Abl-32D cells that require dTTP/dCTP synthesis for survival, thus enabling JMF4073 susceptibility

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RAW 246.7 cells treated with PPADS or iso-PPADS, or MRS2578 in presence of ADA showed significant reduction in expression of inflammatory cytokines such as TGF, and TNF, when compared to ADA alone

Iron homeostasis is closely related to thyroid function, with studies finding that serum iron levels positively correlate with Free Triiodothyronine (FT3) and Free Thyroxine (FT4) levels (14)

Single-cell RNA-seq analysis reveals the Wnt/Ca2+ signaling pathway with inflammation, apoptosis in nucleus pulposus degeneration