This includes those with hypertension, advanced CKD, and those using insulin or metformin
Hypersensitivity reactions may manifest in various ways, ranging from local injection site reactions such as erythema, swelling, and pruritus to more severe systemic reactions including angioedema, anaphylaxis, or generalized urticaria
BioMed Res Int 2021(1):5575245 Lin X (2024) Short-chain fatty acids suppresses astrocyte activation by amplifying Trp-AhR-AQP4 signaling in experimental autoimmune encephalomyelitis mice
Here, microbiome-derived short-chain fatty acids (SCFAs) and anti-inflammatory metabolites can suppress NLRP3 activity by inhibiting ROS production and modulating histone acetylation, promoting tissue homeostasis [31]
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