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[DOI] [PubMed] [Google Scholar] Snyder FR, Davis FC, Henningfield JE

The fact that numerous attempts in this direction have been made, and yet thee is no substitute for tobacco and no de-nicotinized tobacco in general use, is itself a sufficient answer to the question

You may also decide that the risks of treatment outweigh the benefits and opt out of treatment

For example, although EGFR mutations are more common in never-smokers, one-third of lung cancers with EGFR mutations occur in smokers therefore, knowledge of driver mutations and corresponding treatments gleaned from studies of never-smokers may benefit smokers with the disease

Gone Before Her Time: Brittany Murphy 2023, 20:16-20:35