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J Neurol Neurosurg Psychiatry 89:10881100

By inhibiting DPP-4, these drugs prolong incretin activity, leading to: Glucose-dependent insulin secretion from beta cells Suppression of glucagon from alpha cells Improved postprandial blood glucose control This mechanism does not stimulate insulin release in absence of glucose, making hypoglycemia rare

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There are several known side effects of Melanotan II including acne, facial flushing, decreased appetite, and gastrointestinal issues, including diarrhea, nausea, and vomiting

Peptides like BPC-157 for gut healing or CJC-1295 with ipamorelin for lean mass preservation are sometimes stacked with dual agonists