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They found that microbial -diversity decreased as the duration of illness increased, meaning that the variety of gut bacteria reduced over time in individuals with BD (Painold et al., 2019)

Studies have shown that chronic hyperglycemic diets increase the risk of colon cancer, in part by regulating the insulin/IGF-1 signaling axis by activating the downstream PI3K/AKT/mTOR, Ras/MAPK signaling pathways, glucose transporter proteins (GLUT1) and key enzymes of glycolysis (LDHA and HK2), thereby affecting glucose uptake and aerobic glycolysis in cancer cells (65)

Autism Res 2 , 98108 (2009)