microdosing tirzepatide protocol I'm starting a new longevity protocol: Tirzepatide, a dual GLP-1/GIP receptor agonist. Here is the existing evidence, my protocol, measurement plan, and what I expect to achieve by this intervention. 🧵 Microdosing Tirzepatide Program | No

Sources New England Journal of Medicine: Once-Weekly Semaglutide in Adults with Overweight or Obesity New England Journal of Medicine: Tirzepatide Once Weekly for the Treatment of Obesity Diabetes, Obesity and Metabolism: A Journal of Pharmacology and Therapeutics: Semaglutide for the treatment of overweight and obesity: A review JAMA Network: Weight Loss Outcomes Associated With Semaglutide Treatment for Patients With Overweight or Obesity American Diabetes Association: Standards of Medical Care in Diabetes, 2025 Harvard Health Publishing: GLP-1 diabetes and weight-loss drug side effects: Ozempic face and more University of Illinois Chicago: What efficacy data are available on the use of tirzepatide for obesity

Your blood sugar may gradually rise again as appetite and digestion return to baseline

Your metabolic and psychiatric plans should align

Instead you got nausea, confusion about what to eat, and a refrigerator full of foods that suddenly seem impossible to stomach

Elabela may regulate SIRT3-mediated inhibition of oxidative stress through Foxo3a deacetylation preventing diabetic-induced myocardial injury