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Epigenetic mechanisms, such as DNA methylation and histone modifications, have been shown to impact the progression of OA by influencing chondrocyte fate and cartilage homeostasis [105]

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References Sorrell, M.F., Belongia, E.A., Costa, J., et al

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)

This increased cell turnover results in younger-looking skin, better texture, and more even skin tone