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It is worth mentioning that, in normal individuals, it inhibits DA synthesis and release, but when DA neurons are impairedas in the case of Parkinsons diseasethe drug acts as a potent postsynaptic dopamine D2 receptor agonist

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He also led the company through its IPO

Although the pause can be frustrating, emerging real-world data offer reassurance that restarting therapy is often effective when done carefully

Acknowledgements The authors thank their funding agencies, the Singapore Ministry of Health, Ministry of Education and Ministry of Trade, the National Medical Research Council, Singapore, and the Singapore Agency for Science, Technology and Research, for grants NMRC/CSA/0054/2013 (P.M.Y.), NMRC/BNIG/2025/2014 (R.A.S.), IA/I/16/2/502691-Wellcome Trust/DBT India Alliance Intermediate Fellowship (R.A.S.) and NMRC/OFYIRG/0002/2016 (B.K.S.)