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Environ Health Perspect 118:351356

Therefore, while our results provide genetic evidence for associations between smoking-related behaviors and viral hepatitis, they should be interpreted with appropriate caution

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But, as Stein notes, only by doing prospective longitudinal studies can we begin to get at the causal chain here. Stein and colleagues recommend that future studies look at mood disorders as a factor in the relationship between marijuana use and sleep

Because our bodies build up a tolerance against such effects caused by nicotine