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More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

Moreover, the relationship between B12 levels and mood allows for a nuanced understanding of mental health

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A recent UK cross-sectional survey published in the British Journal of General Practice found that self-administered B12 injections are both safe and effective when patients receive proper training with very few complications reported