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While ACh and DA systems clearly both undergo significant maturation in adolescence, thus making them targets of developmental nicotine exposure, a comprehensive understanding of how the maturation of one neuromodulatory system affects the other during this critical period warrants investigation

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Matthews [email protected] This article was submitted to Public Health Education and Promotion, a section of the journal Frontiers in Public Health Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers