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Use with caution in patients with significant dry eye disease, history of significant lid abnormalities/surgeries, or history of nasolacrimal surgery

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Individual results vary based on adherence, dosing, lifestyle factors, and starting weight

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This finding in women is consistent with prior reports suggesting that GLP-1 RAs may produce more pronounced weight loss and glycemic improvements in female people, potentially due to sex-specific differences in GLP-1 receptor expression, pharmacodynamics, or hormonal interactions [21]