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In a study of 252 consecutive patients referred to his clinic for treatment of FMS, Donaldson et al27 found that on complete physical examination, 95 patients had their widespread pain reproduced on digital pressure over primary TrPs and were completely relieved of all their complaints by a course of physical therapy and manual myofascial techniques

GLP-1 medications slow gastric emptying and alter gut motility, which may indirectly affect stool characteristics through changes in transit time and dietary intake

This indicates patients satiety

DiSimone et al., 2004) and cell proliferation (Chen et al., 2000)