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Given the potential for significant health improvements with semaglutide GLP-1 use, many find the investment worthwhile, as it may help in avoiding more expensive medical treatments in the future

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Advantage : CagriSema Glycemic Control# CagriSema : REDEFINE 2 showed 73.5% of T2D patients achieved HbA1c of 6.5% or less, with 13.7% weight loss at 68 weeks

Potential risks include elevated heart rate, high blood pressure, anxiety, insomnia (from phentermine) combined with nausea and GI distress (from semaglutide)

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients