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2 RYBELSUS demonstrated CV safety with no increased risk of MACE 1 Noninferiority of RYBELSUS vs placeboboth in addition to standard of carewas confirmed 1,3,a There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with RYBELSUS Patients were at high CV risk and followed for a relatively short duration (16 months median observation time)

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