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PMID: 25826322

Take, for example, testosterone therapy for women, which is still not FDA-approved for women in the US but offers clear benefits and very little harm when prescribed appropriately

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Lymphocytes B level together with immunoglobulins G (IgG) and immunoglobulins A (IgA) showed a moderate correlation with age at blood drawn, IgG and immunoglobulins M (IgM) are associated with sex and IgG showed a moderate correlation with 2-macroglobulin levels ( Supplementary Tables 5 , 6 )

Wegovy (semaglutide) Summary of Product Characteristics (SmPC)