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Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase

However, they may increase the risk of genital yeast infections

This is known as "Macrophage Polarization." The ability to shift from M1 to M2 efficiently is the Holy Grail of wound repair

But for now, our priority is liver fibrosis, where the need for safe, effective therapies is urgent and growing. With liver disease affecting millions worldwide and few treatments currently available, this Arizona-based innovation may offer a much-needed new path forward