Participants provided written informed consent for use of biosamples for future research, and the ethics committees approved the specific use of the biosamples
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In six healthy (free-living, fertile) US men, a diet with a high Se intake (~200 g/day for ~100 days, mostly through Se-rich beef and rice) decreased concentration and total number of sperm, the proportion of motile, progressive, headless sperm, and tail defects, and increased the proportion of tailless sperm (185)
The approval was based on a series of studies, including a pivotal Phase III trial assessing the vaccines consistency, immunogenicity and safety in healthy adults
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