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Others see slower initial progress that accelerates over time

If you experience severe gastrointestinal symptoms that prevent adequate oral intake, contact your provider promptly, as you may need to delay dose escalation or temporarily adjust your treatment

Retatrutide, Eli Lilly's triple agonist, posted 24.2% body weight loss at the highest dose in Phase 2

The constant worry about when the next flare-up will occur, the anxiety of eating in public, and the stress of managing a diet that is both safe and nourishing can be overwhelming

While many patients experience appetite reduction, it is still important to eat balanced meals and avoid skipping food completely, as this can increase fatigue and worsen side effects